Neisseria Meningitidis ETIOLOGY

-


Neisseria Meningitidis etiology consists of the causative agent which is Neisseria Meningitidis

First of all, Neisseria Meningitidis etiology consists of the causative agent which is Neisseria Meningitidis. In fact, it is small gram-negative diplococcus, aerobic, and possess a polysaccharide capsule, which is the main antigen and determines the serutype of the species. The serogroups of the pathogenic organisms are A, B, C, D, W, Y, Z and L

Neisseria Meningitidis
SCIENTIFIC CLASSIFICATION

Domain: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Neisseriales
Family: Neisseriaceae
Genus: Neisseria
Species: NEISSERIA Meningitidis


Neisseria Meningitidis MORPHOLOGY

  • Capsulated Gram Negative diplococci
  • Length 0.5-1 µm
  • Kidney shaped, flat sides adjacent
  • Intracellular, usually
  • Non-motile
  • Non spore-forming

Neisseria Meningitidis PATHOGENIC ACTION OF FACTORS

Second, the list factors of the pathogenic action of Neisseria Meningitidis are:
  • Biological properties,
  • Promoting attachment of the mucous membrane of nasopharynx depression of symbiotic microflora.
  • Penetration of mucous barriers,
  • Toxic properties and other.

Neisseria Meningitidis CULTURE

  • Growth occur in media enriched with blood or serum.
  • Strict aerobes.
  • Temperature [ 35 – 36 ] degree
  • pH [ 7.4 – 7.6 ]
  • Colony – small(1mm), round , convex, grey, translucent with entire endegs.
  • Chocolate agar is comonly used.

Neisseria Meningitidis PATHOGENESIS

  • It causes pyogenic meningitis in all ages, but is common in children and young adults.
  • Meningococcaemia presets as acute fever with petechial rash.

Neisseria Meningitidis BIOCHEMICAL REACTION

  • Catalase -> Positive
  • Oxisdase -> Positive
  • H2S or idole are not produced.
  • Nitrates are not reduced.

Neisseria Meningitidis RESISTANCE

Third, the resistance of bacterium in the environment are low. For example: Neisseria Meningitidis bacterium perish in the temperature 50°C for 5 minutes, in the temperature 100°C for 30 seconds. In conclusion, Neisseria Meningitidis bacterium can’t resist for low temperature.

Neisseria Meningitidis VIRULENCE FACTORS

Neisseria Meningitidis VIRULENCE FACTORS
Noteworthy, Neisseria Meningitidis has three critical virulence factors:
  • IgA protease. It cleaves the IgA antobides present in respiratory mucosa.
  • The endotoxin of Neisseria Meningitidis is a lipopolysacchalride (LPS). It induces septic shock by causing release of cytokines.
  • Polysaccharride capsule. It is antiphagocytic in nature.

Comments

Post a Comment

Popular posts from this blog

Neisseria Meningitidis SYMPTOMS

-
Firstly, Neisseria Meningitidis symptoms according the prevalence of N. Meningitidis infection, important to know for every human. Neisseria Meningitidis BABY SYMPTOMS Pale. Blotchy complexion. For child is difficult to wake up. Blank and staring expression. Neck retraction with arching of back. Dislike of being handled or fretful. High pitched moaning cry. Whimpering. Refusing feeds. Vomiting. Fever. Cold hands and feets. DEATH RATES OF Neisseria Meningitidis INFECTION BY AGE Secondly, this chart describes interesting information , that from 0 age till 4 age children have biggest risk to be infected. Important question why, which have answer – because of their weak immune system, children can’t protect against infectious disease, therefore we recommend pay strong attention to children health. Neisseria Meningitidis ADULTS SYMPTOMS Thirdly, if you are adult and you want to be calm, that you not have Neisseria M. infectious disease, therefore nee...
Read more

BLACK TEA DEFINITION AND BENEFITS

-
Image
  BLACK TEA BENEFITS Black tea definition and benefits comes from the same plant family as the popular Green and Oolong teas. The main differences between these different types of tea is the level of oxidation in the plants. Black teas are left on the vine the longest before they are picked so they also have the most oxidization and can sometimes have a slightly bitter taste. BLACK TEA BENEFITS: MENTAL ALERTNESS Black teas have the highest level of caffeine of all the teas. This can give a nice jolt and some additional alertness. DENTAL HEALTH Regular consumption of simple black tea has been known to reduce the buildup of plaque. DECREASED STRESS Black and green teas block the neurotransmitter GABA, leading to a decrease in stress response. IMPROVED DIGESTION Black tea reduces inflammation in the digestive tract, making it highly beneficial to anyone with acid reflux or ulcer issues. CANCER PREVENTION Research shows that antioxidants, like polyphenol ...
Read more

HOW TO INCREASE YOUR INFLUENCE AT WORK?

-
Image
HOW TO INCREASE YOUR INFLUENCE AT WORK? DETERMINE WHAT YOU ARE TRYING TO ACHIEVE WHAT ARE YOUR GOALS? WHERE DO YOU WANT TO BE IN 5 YEARS TIME? HOW ARE YOU GOING TO GET THERE Understanding where you are at present, and where you want to be in the future, will help you focus your energy in the right places. KNOW YOUR WORTH THERE IS AN INHERENT LEVEL OF INFLUENCE THAT COMES WITH YOUR ROLE OR JOB TITLE But instead of seeing this as your influence boundary, see it as your influence starting point. BE CONFIDENT IN WHAT YOU HAVE TO OFFER Your knowledge, experience & passion can (and should) be used to your advantage. INFLUENCE AND TRUST GO HAND IN HAND If people do not trust your word or your abilities, you’ll be hard pressed to gain any influence over them. HOW DO YOU CULTIVATE TRUST? By being open & honest at all times. CONSISTENCY IS KEY IF YOU EXECUTE TASKS ACCURATELY, ON TIME, EVERY TIME People will see you as someone they can rely on. ...
Read more